| i-Bio Director | Catherine Jessus |
| i-Bio Deputy Director | Valérie Goguel |
Representatives of core i-Bio labs
| Institut de Biologie Paris-Seine | Michel Labouesse, Director |
| Computational & Quantitative Biology | Martin Weigt (alt. Alessandra Carbone) |
| Neuroscience Paris-Seine | Peter Vanhoutte (alt. Hervé Chneiweiss) |
| Developmental Biology | Sylvie Schneider-Maunoury (alt. Thierry Jaffredo) |
| Biological Adaptation & Ageing | Bertrand Friguet (alt. Rachel Sherrard) |
| Jean Perrin Laboratory | Raphaël Voituriez (alt. Georges Debrégeas) |
| Institut du Fer à Moulin | Jean-Antoine Girault (alt. Fiona Francis) |
Representatives of other disciplines
| Chemistry | Christine Ménager (alt. Roba Moumné) |
| Mathematics | Benoit Perthame |
| Engineering | Guillaume Morel |
| Computer Sciences | Nicolas Bredèche (alt. Benoît Girard) |
Representatives of the University Life Sciences Department
| Director | Sandrine Betuing |
| Scientific board co-presidents | Stéphane Lemaire, Laure Rondi-Reig |